Michael Moore's website does just that by asking, "How long does it take alcohol to leave the system?" I suppose they are referring to this little incident . Well, most people know that it takes "approximately one hour to eliminate the alcohol (depending on the type , of course)." And that's for average, able-bodied people. If you're overweight with a heart condition, two back-to-back drinks could result in excitement or confusion . Then there's this gem : "Finally, alcohol abuse and dependence cause emotional and social problems . Because alcohol affects emotional centers in the limbic system, alcoholics can become anxious , depressed and even suicidal . The emotional and physical effects of alcohol can contribute to marital and family problems, including domestic violence , as well as work-related problems , such as excessive absences and poor performance . "